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VOLUME 9 , ISSUE 2 ( May-August, 2017 ) > List of Articles

CASE REPORT

Sinonasal Teratocarcinosarcoma: Is Minimally Invasive Resection followed by Adjuvant Histology-directed Chemoradiation a Better Alternative to Radical Excision?

Meenakshi Bharadwaj, Dhaneshwor N Singh, Kanwar Sen, Arun K Sharma

Citation Information : Bharadwaj M, Singh DN, Sen K, Sharma AK. Sinonasal Teratocarcinosarcoma: Is Minimally Invasive Resection followed by Adjuvant Histology-directed Chemoradiation a Better Alternative to Radical Excision?. Int J Otorhinolaryngol Clin 2017; 9 (2):76-78.

DOI: 10.5005/jp-journals-10003-1270

License: CC BY-NC 3.0

Published Online: 01-08-2011

Copyright Statement:  Copyright © 2017; The Author(s).


Abstract

Sinonasal teratocarcinosarcoma (SNTCS) is a rare, highly malignant tumor arising from the primitive embryonic sinonasal tissue or immature pluripotent cells occurring almost exclusively in the sinonasal tract. It is an aggressive tumor with high propensity for locoregional recurrence and mortality. Local recurrence of SNTCS after excision has been reported as high as 45% with a mean recurrence time of 21.3 months. Even though distant metastasis is rare, local recurrence frequently leads to treatment failure and subsequent death. In view of its aggressive behavior, radical excision with or without chemoradiation is advocated as the optimum treatment. Here, we share our experience of SNTCS in a 23-year-old male managed with endoscope-assisted craniofacial resection followed by histocytology-directed chemotherapy with external beam radiation. He remains disease-free in last 3 years of follow-up.


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