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VOLUME 7 , ISSUE 1 ( January-April, 2015 ) > List of Articles

CASE REPORT

Glial Heterotopia of Sphenoid in Association with a Patent Sternberg's Canal presenting with Meningitis

R Suma, KJ Jeena, VM Pavithran, A Govindan

Citation Information : Suma R, Jeena K, Pavithran V, Govindan A. Glial Heterotopia of Sphenoid in Association with a Patent Sternberg's Canal presenting with Meningitis. Int J Otorhinolaryngol Clin 2015; 7 (1):23-25.

DOI: 10.5005/aijoc-7-1-23

License: CC BY-NC 3.0

Published Online: 01-03-2013

Copyright Statement:  Copyright © 2015; The Author(s).


Abstract

Ectopic glial tissue, presenting at various sites of body is a rare embryonic developmental anomaly. Very few cases are reported in adults, most being incidentally detected, revealed only by histopathological findings. One of the rarest locations is the sphenoid sinus.

We present here the case of a middle aged female, presenting with spontaneous cerebrospinal fluid (CSF) rhinorrhea and meningitis. With the radiological finding of a soft tissue density in sphenoid sinus with erosion of left temporal skull base, she underwent lateral craniotomy, with excision of the mass and middle cranial fossa floor repair. Histopathology revealed a heterotopic glial tissue. Peroperative finding of a well-defined defect in the lateral wall of an extensively pneumatized sphenoid showed typical features of a patent Sternberg's canal.

This case could be a living proof for the existence of this rare developmental anomaly. A persisting Sternberg's canal should be considered as the source of spontaneous CSF leaks with or without lesions in sphenoid sinuses with extensive lateral pneumatization. Most of the cases may be treated with an extended endoscopic approach. Extreme lateral lesions like this would benefit most from a craniotomy approach for proper closure of skullbase defect. Three years after successful surgery, she remains symptom free.


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  1. Nasal astrocytoma or nasal glial heterotopia? Arch Pathol Lab Med 1989;113(8):943–945.
  2. Central nervous system tissue heterotopia of the nose: case report and review of the literature. ACTA Otorhinolaryngologica Italica 2009;29(4):218–221.
  3. Tumours of the head and neck: clinical and pathological considerations; 2nd edn. Williams and Wilkins Co, Baltimore; 1979. p. 16.
  4. Nasal glial heterotopia. Arch Pathol Lab Med 2000 Dec;124(12):1849.
  5. Extranasal glial heterotopia: case report. Neurology India 2003;51(2):248–249.
  6. Tumors of the central nervous system. AFIP Atlas of tumor pathology. Series 4. Washington, DC: American Registry of Pathology; 2007. p. 492–493.
  7. Nasalglioma or nasal glial heterotopia? Morphological immunohistochemical and ultrastructural study of two cases. Clin Neuropathol 2002 Mar-Apr;21(2):66–71.
  8. Nasal glial heterotopia: a clinicopathologic and immunophenotypic analysis of 10 cases with a review of the literature. Ann Diagn Pathol 2003;7(6):354–359.
  9. Endonasal endoscopic repair of Sternberg's canal cerebrospinal, fluid leaks. Laryngoscope 2007;117(2):345–349.
  10. A rare case of nasal glioma in the sphenoid sinus of an adult presenting with meningoencephalitis. Eur Archives of Otorhinolaryngol 2005; 262(7):592–594.
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