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VOLUME 6 , ISSUE 4 ( Number, 2014 ) > List of Articles

RESEARCH ARTICLE

Effects of Radiotherapy on Auditory and Vestibular Function

Sachin Sharad Nilakhe

Citation Information : Nilakhe SS. Effects of Radiotherapy on Auditory and Vestibular Function. Int J Otorhinolaryngol Clin 2014; 6 (4):1-5.

DOI: 10.5005/aijoc-6-4-1

License: CC BY-NC 3.0

Published Online: 01-09-2012

Copyright Statement:  Copyright © 2014; The Author(s).


Abstract

Introduction

Radiotherapy either primary or adjuvant, is a commonly used modality of treatment in head and neck malignancies. The audiovestibular apparatus is often within the fields of radiation treatment, and hearing loss is a possible complication. This study was undertaken to assess the audiovestibular functions in patients undergoing radiation therapy for head and neck malignancies to determine the type and severity of hearing loss and vestibular dysfunction following radiation therapy.

Materials and methods

Fifty patients with head and neck malignancies reported to the malignant disease treatment center of INHS Asvini and received radiotherapy as a primary modality of treatment or in combination with surgery during the period May 2003 to Sep 2004 were included in this study. None of these patients had prior treatment by chemotherapy.

Conclusion

A significant number of patients who were subjected to radiation therapy for head and neck malignancies develop conductive hearing loss is predominant in the immediate postradiation period. Conductive hearing loss is reversible and improves with the conservative line of treatment. Sensorineural hearing loss more commonly affects the higher frequencies and is more common in older patients. Sensorineural hearing loss is more common when radiation doses exceed 60 Gy. There is no conclusive evidence of vestibular dysfunction in patients undergoing radiotherapy for head and neck cancers.


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  1. Long-term sensorineural hearing loss following radiotherapy in patients suffering from nasopharyngeal carcinoma. Head and Neck 1999;21(6):547–553.
  2. Radiation dose to otologic structures during head and neck cancer radiation therapy. Head and Neck Surgery 2000;110(3):217–221.
  3. Hearing anomalies following radiation therapy for head and neck cancers. Indian J Exp Biol 1996 Sep;34(9):878–879.
  4. Radiation induced changes in the middle ear mucosa. J Otolaryngol 1985;99(4):343–353.
  5. X-ray irradiation of inner ear of guinea pig. Early degenerative changes in the sensory epithelia. Acta Otolaryngol (Stockh) 1969;68(6):514–525.
  6. Late audiovestibular consequences of radical radiotherapy to the parotid. Clin Oncol R Coll Radiol 1991;3(4):217–219.
  7. Vestibular apparatus disorders after external radiation thrapy for head and neck cancers. Radither Oncol 1992 Sept 25;23(1):25–30.
  8. Caloric response and postural control in patients with nasopharyngeal carcinoma after radiation therapy. Clin Otolaryngol 1998;23(5):439–441.
  9. Delayed damage of ionizing radiation on the inner ear. Zhonghua Er Bi Yan Hou Ke Za Zhi 1997 Aug;32(4):222–225.
  10. The effects of ionizing radiation on the ear. Annal Otorhinolaryngol 1961;70:255–261.
  11. Pathology of the nervous system: the effects of atomic radiation. Minchler J Ed 1968;76(2):892.
  12. Effects of ionizing radiation on hearing. JAMA 1935;20(4):263.
  13. Irradiation of the ear. J Laryngol Otol 1965;79(10):870–880.
  14. Effects of the hearing of the patients treated by irradiation in the head and neck area. J Laryngol and Otology 1966;80(3):276–287.
  15. Sensorineural hearing loss following radiotherapy to the nasopharynx. Laryngoscope 1976;86(4):598–602.
  16. Sensorineural hearing loss in patients treated with irradiation for nasopharyngeal carcinoma. Ind J Radiat Oncol Biol Phys 1995 Aug;21(3):723–728.
  17. Radionecrosis of the temporal bone. Laryngoscope 1976;86(3):598–602.
  18. Mechanism of hearing loss in irradiated ears: a long-term longitudinal study. Ann Otol Rhinol Laryngol 2001 Oct;110(10):904–906.
  19. Radiation induced hearing loss. Am J Surg 1994;168(5):408–411.
  20. Sensorineural hearing loss in patients undergoing radiation and cisplatin treatment. Int J Radiat Oncol Biol Phys 1996;36(2):515–517.
  21. Radiation necrosis of the ossicles. Arch Otolaryng 1960;71:793–796.
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