An International Journal of Otorhinolaryngology Clinics

Register      Login

VOLUME 6 , ISSUE 3 ( Number, 2014 ) > List of Articles

CASE REPORT

Extramedullary Plasmacytoma of Head and Neck Region: Report of Six Cases with Different Localizations

Kerem Öztürk, Mustafa Şahin, Raşit Midilli, Gülce Gürsan, Nazan Özsan, Recep Savaş

Citation Information : Öztürk K, Şahin M, Midilli R, Gürsan G, Özsan N, Savaş R. Extramedullary Plasmacytoma of Head and Neck Region: Report of Six Cases with Different Localizations. Int J Otorhinolaryngol Clin 2014; 6 (3):10-16.

DOI: 10.5005/aijoc-6-3-10

License: CC BY-NC 3.0

Published Online: 01-09-2012

Copyright Statement:  Copyright © 2014; The Author(s).


Abstract

Extramedullary plasmacytoma (EMP) is a rarely seen neoplasm of plasma cells which may be locally destructive by involving submucosal soft tissues of upper respiratory tract but without systemic dissemination. It comprises less than 1% of head and neck malignities. Clinical presentation depends on tumor's effect and its involvement site. Diagnosis is made with histopathologic examination of tissue biopsy. Responses to its treatment with local radiotherapy and surgery are similar. In this article; it is intended to update our knowledge regarding EMP and remind this rarely encountered disease by presenting various cases detected in nasopharynx, tonsil, buccal mucosa, larynx, mastoid cavity and sphenoid sinus, with literature line.


PDF Share
  1. Clinical outcome of extramedullary plasmacytoma. Haematologica 2000;85:47–51.
  2. Solitary plasmacytomas of bone and extramedullary plasmacytomas. A clinicopathologic and immunohistochemical study. Cancer 1987;59:1475–1485.
  3. Extramedullary plasmacytoma of the head and neck. Laryngoscope 1964;74:553–559.
  4. Extramedullary plasmacytoma of the head and neck region: Clinicopathological correlation in 25 cases. Br J Cancer 1997;75:921–927.
  5. Extramedullary laryngeal plasmacytoma. Ann Otol Rhinol Laryngol 1996;105:483–486.
  6. Extramedullary plasmacytoma of the head and neck: a clinicopathologic study of 20 cases. Medicine 1982;61:317–329.
  7. Extramedullary plasmacytoma of paranasal sinuses. A combined therapeutic strategy. Acta Otorhinolaryngol Ital 2006;26: 118–120.
  8. Definitive radiotherapy for extramedullary plasmacytomas of the head and neck. Br J Radiol 2003;76:738–741.
  9. Extramedullary plasmacytomas of the head and neck. Otolaryngol Head Neck Surg 1993;109:877–885.
  10. A case of extramedullary plasmacytoma arising from the nasal septum. J Laryngol Otol 2000;114:53–55.
  11. CT findings in a nasopharyngeal extramedullary plasmacytoma. J Comput Assist Tomogr 1983;7:1081–1083.
  12. World Health Organization Classification of neoplastic diseases of the hematopoietic and lymphoid tissues: a progress report. Am J Clin Pathol 1999;111:8–12.
  13. Extramedullary plasmacytoma of the parotid. Head Neck 1990;12:352–354.
  14. Primary extramedullary plasmacytoma of the liver: a case report. Am J Surg Pathol 1995;19:1197–1202.
  15. Extramedullary plasmacytoma mimicking primary colonic carcinoma in a patient with Crohn's disease: case report and literature review. Arch Pathol Lab Med 1996;120:279–282.
  16. Plasma cell tumors of the upper respiratory tract. A clinicopathologic study with emphasis on criteria for histogic cliagnosis. Am J Pathol 1950;26:445–461.
  17. The natural history of extramedullary plasmacytoma and its relation to solitary myeloma of bone and myelomatosis. Medicine 1976;55:217–238.
  18. Extramedullary plasmacytoma: clinical behavior and response to treatment. Ann Oncol 1992;3:51–57.
  19. Myeloma and plasmacytomas. In: Perez CA, Brady LW, editors. Principles and Practice of Radiation Oncology. 3th ed. Philadelphia Lippincott-Raven Publishers. 1997. p. 2013–2023.
  20. Multiple myeloma involving the thyroid cartilage: case report. Am J Neuroradiol 2002;23:316–318.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.