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VOLUME 2 , ISSUE 3 ( September-December, 2010 ) > List of Articles


Malignant Transformation of Nonirradiated Recurrent Juvenile Laryngeal Papillomatosis

Jagadish Tubachi, Arsheed Hussain Hakeem, Rajay Ramesh Kumar, Satish Pawar

Keywords : Juvenile laryngeal papillomatosis,Malignant transformation,Squamous cell cancer

Citation Information : Tubachi J, Hakeem AH, Kumar RR, Pawar S. Malignant Transformation of Nonirradiated Recurrent Juvenile Laryngeal Papillomatosis. Int J Otorhinolaryngol Clin 2010; 2 (3):259-261.

DOI: 10.5005/jp-journals-10003-1047

Published Online: 01-08-2011

Copyright Statement:  Copyright © 2010; The Author(s).


Very few cases of spontaneous malignant transformation of nonirradiated recurrent juvenile laryngeal papillomatosis (JLP) have been reported in literature. We document a case of invasive laryngeal carcinoma arising in pre-existing juvenile laryngeal papillomatosis. After multiple CO2 Laser resections, a 29-year-old female, non-smoker, who had never received radiation therapy, developed a florid exophytic transglottic squamous cell carcinoma. Therefore, regular extensive biopsies and careful histopathological examination are required in cases of JLP. We also emphasize the need to maintain a high index of suspicion for malignant transformation in long standing cases.

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