Congenital granular cell tumor (CGCT), or congenital epulis (CE), is an uncommon benign soft tissue lesion that usually arises from the alveolar mucosa of neonates. It can be found in the jaw, skin, gastrointestinal, and respiratory tract. It is seen more frequently in female neonates. It can sometimes lead to feeding and respiratory problems. The etiology is unknown although origin from vascular pericytes or smooth muscle is speculated. As most of the granular cell tumors are benign, surgical excision of the lesion is the treatment of choice. We here present a case report of a 14-hour-old female infant, who had a solitary mass on the anterior maxillary alveolar ridge. The lesion, which was histologically a CGCT, was removed completely by simple excision.
Kim SK, Won HS, Lee SW, et al. Prenatal diagnosis of congenital epulis by three-dimensional ultrasound and magnetic resonance imaging. Prenat Diagn 2006;26(2):171–174. DOI: 10.1002/pd.1368.
Gokhale UA, Malhotra CJ. Congenital epulis of the newborn. Indian J Pathol Microbiol 2009;52(3):436–437. DOI: 10.4103/0377-4929. 55020.
Kannan SK, Rajesh R. Congenital epulis – congenital granular cell lesion: A case report. J Indian Soc Pedod Prev Dent 2006;24(2): 104–106. DOI: 10.4103/0970-4388.26026.
Silva GC, Vieira TC, Vieira JC, et al. Congenital granular cell tumor (congenital epulis): A lesion of multidisciplinary interest. Med Oral Patol Oral Cir Bucal 2007;12(6):E428–E430. PMID: 17909507.
Neville BW, Damm DD, Allen CM, et al. Oral and Maxillofacial Pathology. 3rd edition. St Louis: Saunders/Elsevier; 2009. pp. 537–539.
Fister P, Volavsek M, Novosel Sever M, et al. A newborn baby with a tumor protruding from the mouth. Acta Dermatovenerol Alp Panonica Adriat 2007;16(3):128–130. PMID: 17994174.
Zarbo RJ, Lloyd RV, Beals TF, et al. Congenital gingival cell tumor with smooth muscle cyto differentiation. Oral Surg Oral Med Oral Pathol 1983;56(5):512–520. DOI: 10.1016/0030-4220(83)90099-3.
Ritwik P, Brannon RB, Musselman RJ. Spontaneous regression of congenital epulis: A case report and review of the literature. J Med Case Rep 2010;4:331. DOI: 10.1186/1752-1947-4-331.