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VOLUME 16 , ISSUE 1 ( January-April, 2024 ) > List of Articles

Original Article

Clinicopathological Correlation of Sinonasal Masses in North-East Indian Population in a Tertiary Care Hospital

Suvamoy Chakraborty, Ratan Medhi, Neizekhotuo B Shunyu, Manu Coimbatore Balakrishnan, Zareen A Lynrah, Prachurya Tamuli, Vandana Raphael

Keywords : Clinicopathological correlation, North-Eastern Indian population, Observational cross-sectional study, Polyp, Sinonasal mass

Citation Information : Chakraborty S, Medhi R, Shunyu NB, Balakrishnan MC, Lynrah ZA, Tamuli P, Raphael V. Clinicopathological Correlation of Sinonasal Masses in North-East Indian Population in a Tertiary Care Hospital. Int J Otorhinolaryngol Clin 2024; 16 (1):8-13.

DOI: 10.5005/jp-journals-10003-1509

License: CC BY-NC 4.0

Published Online: 11-04-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Aims: To find out the correlation between clinical diagnosis and pathological diagnosis of various sinonasal masses in the North-East Indian Population. Materials and methods: This study is a hospital-based observational cross-sectional study done over a period of 1 year (2020–2021) in the ENT department of a tertiary care Hospital, in North-Eastern India. A total of 40 patients who presented with sinonasal masses to the ENT OPD of our hospital were included in the study. After a detailed clinical history and examination; nasal endoscopy, radiological investigations and biopsy (wherever indicated) were performed. Whenever any surgical procedure was done, the tissue was sent for histopathological examination (HPE). Results: In our study, in 31 cases (77.5%), the clinical and pathological diagnoses were the same, whereas in 9 cases (22.5%), there was discrepancy between clinical and pathological diagnosis. This correlation was statistically significant with p-value of 0.001. Conclusion: We conclude that by thorough clinical, endoscopic, and radiological evaluation we can come to a provisional diagnosis but HPE is necessary to confirm the diagnosis and hence helps in the proper and early treatment of sinonasal mass. Clinical significance: Knowledge of the clinicopathological correlation of sinonasal mass in the North-Eastern Indian population will take us a long way in improving the quality of medical care in this region.

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  1. Neb V, Bhagat V, Patel PR, et al. Spectrum of neoplastic sino-nasal lesions at tertiary care centre. Indian J Pathol Oncol 2020;7(1):104–108. DOI:10.18231/j.ijpo.2020.020.
  2. Kulkarni AM, Mudholkar VG, Acharya AS, et al. Histopathological study of lesions of nose and paranasal sinuses. Indian J Otolaryngol Head Neck Surg Off Publ Assoc Otolaryngol India 2012;64(3):275–279. DOI: 10.1007/s12070-011-0286-7.
  3. Rokade V, Shinde KJ, More GR. Clinicopathological profile of sinonasal masses-a tertiary care centre study in rural India. Int J Otorhinolaryngol Head Neck Surg 2020;6(10):1821. DOI: 10.18203/issn.2454-5929.ijohns20204182.
  4. Sahni D, Kaur G, Verma P, et al. Clinico-pathological and radiological correlation of sino-nasal masses in a tertiary care center. Int J Otorhinolaryngol Head Neck Surg 2020;6(7):1342. 10.18203/issn.2454-5929.ijohns20202790.
  5. Lathi A, Syed MMA, Kalakoti P, et al. Clinico-pathological profile of sinonasal masses: A study from a tertiary care hospital of India. ACTA Otorhinolaryngologica Italica 2011;31(6):372–377. PMID: 22323848.
  6. Sivalingam J, Sarawagi R, Raghuwanshi S, et al. Sinonasal neoplasia – clinicopathological profile and importance of computed tomography. J Clin Diagn Res JCDR 2015;9(6):TC01–TC04. DOI: 10.7860/JCDR/2015/13514.6026.
  7. Rawat DS, Chadha V, Grover M, et al. Clinico-pathological profile and management of sino-nasal masses: A prospective study. Indian J Otolaryngol Head Neck Surg 2013;65(Suppl 2):388–393. DOI: 10.1007/s12070-012-0578-6.
  8. Bakari A, Afolabi OA, Adoga AA, et al. Clinico-pathological profile of sinonasal masses: An experience in national ear care center Kaduna, Nigeria. BMC Res Notes 2010;3(1):186. DOI: 10.1186/1756-0500-3-186.
  9. Makhasana JAS, Kulkarni MA, Vaze S, et al. Juvenile nasopharyngeal angiofibroma. J Oral Maxillofac Pathol 2016;20(2):330. DOI: 10.4103/0973-029X.185908.
  10. Bhattacharya J, Goswami BK, Banerjee A, et al. A clinicopathological study of masses arising from sinonasal tract and nasopharynx in north Bengal population with special reference to neoplasms. Egypt J Otolaryngol 2015;31(2):98–104. DOI: 10.4103/1012-5574.156091.
  11. Settipane GA. Epidemiology of nasal polyps. Allergy Asthma Proc 1996;17(5):231–236. DOI: 10.2500/108854196778662246.
  12. Agarwal P, Panigrahi R. Sinonasal mass—a recent study of its clinicopathological profile. Indian J Surg Oncol 2017;8(2):123–127. DOI: 10.1007/s13193-016-0570-9.
  13. Mahajan N, Nagose V, Vaze V, et al. Clinicopathological study of nasal masses – A two years retrospective study. MedPulse Int J Pathol 2020;16(2):11–15. DOI: 10.26611/1051622.
  14. Singh SG, Qureshi S, Jain L, et al. Presentation of lesions of nose and paranasal sinuses at a tertiary care center in Central India. Indian J Otolaryngol Head Neck Surg Off Publ Assoc Otolaryngol India 2018;70(2):284–289. DOI: 10.1007/s12070-018-1246-2.
  15. Bist S, Kusum A, Varshney S, et al. Clinico-pathological profile of sinonasal masses: An experience in tertiary care hospital of Uttarakhand. Natl J Maxillofac Surg 2012;3(2):180. DOI: 10.4103/0975-5950.111375.
  16. Garg D, Mathur K. Clinico-pathological study of space occupying lesions of nasal cavity, paranasal sinuses and nasopharynx. J Clin Diagn Res JCDR 2014;8(11):FC04–FC07. DOI: 10.7860/JCDR/2014/10662.5150.
  17. Dua K, Chopra N, Mittal V, et al. Histopathology of Nasal Masses. Int J Clin Rhinol 2010;3(2):81–85. DOI: 10.5005/jp-journals-10013-1033.
  18. Gupta R, Moupachi SS, Poorey VK. Sinonasal masses: A retrospective analysis. Indian J Otolaryngol Head Neck Surg 2013;65(1):52–56. DOI: 10.1007/s12070-012-0602-x.
  19. Hasan A, Nady M, Ibrahim AA, et al. The utility of clinicopathological correlation of sinonasal masses in a tertiary hospital. J Evol Med Dent Sci 2021;10(10):679–683. DOI: 10.14260/jemds/2021/146.
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