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VOLUME 12 , ISSUE 2 ( May-August, 2020 ) > List of Articles


Functional Rejuvenation of Recurrent Laryngeal Nerve after Excision of Parathyroid Cyst: A Case Report and Systematic Review of Literature

N Vishnu S Reddy, Manoj Sharma, Murali Chintham, Priyanka Sharma

Keywords : Carotid sheath, Hoarseness of voice, Neck cyst, Parathyroid cyst, Vocal cord palsy, Whole parathyroid hormone (wPTH) assays

Citation Information : Reddy NV, Sharma M, Chintham M, Sharma P. Functional Rejuvenation of Recurrent Laryngeal Nerve after Excision of Parathyroid Cyst: A Case Report and Systematic Review of Literature. Int J Otorhinolaryngol Clin 2020; 12 (2):31-34.

DOI: 10.5005/jp-journals-10003-1351

License: CC BY-NC 4.0

Published Online: 03-03-2021

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Vocal fold paralysis is a prevalent manifestation of various disorders inclusive of the commonest conditions, such as, cardiothoracic surgeries, head and neck malignancies, whereas parathyroid cysts and cervical osteophytes are the rarest causes of this common presentation. A comprehensive systematic review of the literature was done with keyword “parathyroid cysts causing vocal fold palsy” using MEDLINE, PubMed, additionally following PRISMA 2009 guidelines. A 59-year-old male patient presented with hoarseness of voice with right-sided neck swelling for one year. Excision of swelling adherent to the carotid sheath was done. Postoperative histopathological and biochemical analysis of aspirated fluid was consistent with the parathyroid cyst. Patient is in regular follow-up, and there are no clinical signs of recurrence and there is normal functioning of the affected vocal cord. This report adds to the growing knowledge of rare parathyroid cysts with unusual presentations, along with an understanding of pathophysiology, clinical diagnosis, and recovery options for vocal fold palsy due to lesions in the parathyroid gland.

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  1. Vocal fold immobility: a longitudinal analysis of etiology over 20 years. Laryngoscope 2007;117:1864–1870. DOI: 10.1097/MLG.0b013e3180de4d49.
  2. General thoracic surgery. Philadelphia: Lippincott Williams & Wilkins; -21Dec-2011. page no 2546.
  3. Parathyroid cysts: diagnosis and management. Laryngoscope 2001;111(9):1576–1578. DOI: 10.1097/00005537-200109000-00015.
  4. First parathyroid surgeon: Sir John Bland-Sutton and the parathyroids. ANZ J Surg 2007;77(12):1058–1061. DOI: 10.1111/j.1445-2197.2007.04324.x.
  5. Parathyroid cysts; report of five cases. Surgery 1953;14:151–154.
  6. Recurrent nerve palsy due to parathyroid cyst. Int Surg 1991;76(3):192–193.
  7. Benign thyroid disease and vocal cord palsy. Ann R Coll Surg Engl 1993;75(4):241–244.
  8. Recurrent laryngeal nerve paralysis by compression from a tracheal diverticulum. Ann Thorac Surg 2014;97(3):1068–1071. DOI: 10.1016/j.athoracsur.2013.06.118.
  9. Cervical osteophytes causing vocal fold paralysis: case report and literature review. J Laryngol Otol 2012;126(9):963–965. DOI: 10.1017/S0022215112001259.
  10. Vocal fold mobility alteration reversed after thyroidectomy. Autops Case Rep 2016 Sep 30;6(3):53–57. DOI: 10.4322/acr.2016.039.
  11. Congenital neck masses. Embryonic origin and diagnosis. Report of the CIREOL. J Radiol 1995;76(7):405–415.
  12. A single-institution 25-year review of true parathyroid cysts. Langenbecks Arch Surg 2006;391(1):13–18. DOI: 10.1007/s00423-005-0579-y.
  13. Parathyroid cyst: the forgotten diagnosis of a neck mass. J Surg Case Rep 2011;2011(8):4. DOI: 10.1093/jscr/2011.8.4.
  14. Parathyroid hormone/parathyroid hormone-related peptide receptor 1 expression in odontogenic cystic lesions. Int Endod J 2012;45(3):209–214. DOI: 10.1111/j.1365-2591.2011.01961.x.
  15. A benign parathyroid cyst presenting with hoarse voice. J Laryngol Otol 2000;114(2):147–148. DOI: 10.1258/0022215001904923.
  16. Benign parathyroid cyst causing vocal fold paralysis: a case report and review of the literature. Head Neck 2006;28(6):564–566. DOI: 10.1002/hed.20391.
  17. Vocal fold paralysis secondary to a benign parathyroid cyst: a case report with clinical, imaging and pathological findings. Eur Radiol 2008;18(9):2015–2018. DOI: 10.1007/s00330-008-0919-8.
  18. Parathyroid cyst. Am Surg 2015;81:163–165.
  19. Parathyroid cyst with recurrent vocal fold paresis. Aust N Z J Surg 1993;63(7):561–562. DOI: 10.1111/j.1445-2197.1993.tb00453.x.
  20. Parathyroid cyst, a rare cause of cystic cervical lesion. Case report. Med Ultrason 2011;13(2):157–160.
  21. Functional parathyroid cyst: a rare cause of malignant hypercalcinemia with primary hyperparathyroidism – a case report and review of literature. Case Rep Med 2012;2012: 851941. DOI: 10.1155/2012/851941.
  22. Small nonfunctional parathyroid cysts: single institution experience. Endocr J 2017;64(2):151–156. DOI: 10.1507/endocrj.EJ16-0398.
  23. Vocal cord palsy secondary to parathyroid cyst in the young: rare case report with review of the literature. J Head Neck Physicians Surg 2017 Jul–Dec;5(2):90. DOI: 10.4103/jhnps.jhnps̲24̲17.
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