An International Journal of Otorhinolaryngology Clinics

Register      Login

VOLUME 12 , ISSUE 1 ( January-April, 2020 ) > List of Articles


Giant Pleomorphic Adenoma of the Parotid Gland: A Case Report

Ritu Gupta, Sunil Kumar, Sameer Saraf

Keywords : Parotid gland, Parotid tumors, Pleomorphic adenoma

Citation Information : Gupta R, Kumar S, Saraf S. Giant Pleomorphic Adenoma of the Parotid Gland: A Case Report. Int J Otorhinolaryngol Clin 2020; 12 (1):17-19.

DOI: 10.5005/jp-journals-10003-1347

License: CC BY-NC 4.0

Published Online: 03-03-2021

Copyright Statement:  Copyright © 2020; The Author(s).


The tumors of the salivary gland are rare but the most common is pleomorphic adenoma (PA). Since PA is asymptomatic, it is ignored by the patients until they are cosmetically bothered. A 57-year-old male presented to us with a large growth on the right side of the face, which enlarged gradually over a period of over 10 years. The excised specimen was 27 cm × 17 cm × 10 cm in dimensions and 2.250 kg in weight.

  1. Phillips DE, Jones AS. Reliability of clinical examination in the diagnosis of parotid tumors. J R Coll Surg Edinb 1994;39(2):100–102. PMID: 7520060.
  2. Buenting JE, Smith TL, Holmes DK. Giant pleomorphic adenoma of the parotid gland: case report and review of the literature. Ear Nose Throat J 1998;77(8):634, 637–638, 640. DOI: 10.1177/014556139807700812.
  3. Duck SW, McConnel FM. Malignant degeneration of pleomorphic adenoma—clinical implications. Am J Otolaryngol 1993;14(3): 175–178. DOI: 10.1016/0196-0709(93)90026-4.
  4. Ellis GL, Auclair PL, editors. Atlas of tumor pathology. Tumours of the salivary glands. Washington, DC: Armed Forces Institute of Pathology; 1995. pp. 39–41. DOI: 10.1002/1096-9896(200012)192:4<564::AID-PATH737>3.0.CO;2-M.
  5. Spence J. Case of enormous deep-seated tumour of the face and neck, successfully removed by operation plates. Dublin J Med Sci 1863;36:272–283. DOI: 10.1007/BF02944021.
  6. Short DW, Pullar P. Giant parotid tumors: with report of a case. J R Coll Surg Edinb 1956:1(3):240–248.
  7. Schultz-Coulon HJ. Pleomorphic giant adenomas of the parotid gland. Laryngorhinootologie 1989;68(8):445–449. DOI: 10.1055/s-2007-998373. PMID: 2551308.
  8. Auclair PL, Ellis GL. Atypical features in salivary gland mixed tumors: their relationship to malignant transformation. Mod Pathol 1996;9(6):652–657. PMID: 8782203.
  9. Yamamoto Y. Clinical signs and histology of carcinoma in pleomorphicadenoma. Otologia 1994;87:1320–1324.
  10. Eneroth CM, Zettterberg A. Malignancy in pleomorphic adenoma. A clinical and microspectrophotometric study. Acta Otolaryngol 1974;77(6):426–432. DOI: 10.3109/00016487409124645.
  11. Milašin J, Pujić N, Dedović N, et al. H-ras gene mutations in salivary gland pleomorphic adenomas. Int J Oral Maxillofac Surg 1993;22(6):359–361. DOI: 10.1016/s0901-5027(05)80668-x.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.