An International Journal of Otorhinolaryngology Clinics

Register      Login

VOLUME 11 , ISSUE 3 ( September-December, 2019 ) > List of Articles


Nodulisporium: An Extremely Rare Cause of Allergic Fungal Rhinosinusitis

Shasikala Suthersan, Ratna Mohd Tap, Haslinda Md Taha, Boon C Gan

Citation Information : Suthersan S, Tap RM, Taha HM, Gan BC. Nodulisporium: An Extremely Rare Cause of Allergic Fungal Rhinosinusitis. Int J Otorhinolaryngol Clin 2019; 11 (3):70-72.

DOI: 10.5005/jp-journals-10003-1339

License: CC BY-NC 4.0

Published Online: 02-03-2021

Copyright Statement:  Copyright © 2019; The Author(s).


The world of rhinology has smelt and dealt with a steadily increasing number of allergic fungal rhinosinusitis cases that were initially mistaken for chronic rhinosinusitis. Although both group of patients present similarly, the allergic fungal counterpart does not respond to conventional medical therapy. We report a case of a young gentleman who combated chronic rhinosinusitis for years before undergoing functional endoscopic sinus surgery which yielded an extremely rare fungal pathogen, Nodulisporium species, clinching the diagnosis of allergic fungal rhinosinusitis. Operative intervention was key to definitive diagnosis and treatment for this case. We discuss the challenges and methods used in identifying Nodulisporium, the surgical approach, and procedures performed in treating this condition.

  1. Cox GM, Schell WA, Scher RL, et al. First report of involvement of Nodulisporium species in human disease. J Clin Microbiol 1994;32(9):2301–2304. DOI: 10.1128/JCM.32.9.2301-2304.1994.
  2. Schell WA. Unusual fungal pathogens in fungal rhinosinusitis. Otolaryngol Clin North Am 2000;33(2):367–373. DOI: 10.1016/S0030-6665(00)80011-0.
  3. Umabala P, Lakshmi V, Murthy AR, et al. Isolation of a Nodulisporium species from a case of cerebral phaeohyphomycosis. J Clin Microbiol 2001;39(11):4213–4218. DOI: 10.1128/JCM.39.11.4213-4218.2001.
  4. DeShazo RD, Swain RE. Diagnostic criteria for allergic fungal sinusitis. J Allergy Clin Immunol 1995;96(1):24–35. DOI: 10.1016/S0091-6749(95)70029-3.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.