Citation Information :
Singh DN, Sen K, Sharma AK, Bharadwaj M. Sinonasal Teratocarcinosarcoma: Is Minimally Invasive Resection Followed by Adjuvant Histology-directed Chemoradiation a Better Alternative to Radical Excision? A Case Report. Int J Otorhinolaryngol Clin 2019; 11 (1):9-11.
Sinonasal teratocarcinosarcoma (SNTCS) is a rare, highly malignant tumor arising from primitive embryonic sinonasal tissue or immature pluripotential cells occurring almost exclusively in the sinonasal tract. It is an aggressive tumor with a high propensity for locoregional recurrence and mortality. Local recurrence of SNTCS after excision has been reported as high as 45% with a mean recurrence time of 21.3 months. Even though distant metastasis is rare, local recurrence frequently leads to treatment failure and subsequent death. In view of its aggressive behavior, radical excision with or without chemoradiation is advocated as the optimum treatment. Here we share our experience of SNTCS in a 23-year-old man managed with endoscope assisted craniofacial resection followed by histocytology-directed chemotherapy with external beam radiation. He remains disease-free in the last 3 years of follow-up.
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